A 58-year-old man had a large, white, preretinal lesion in the inferior macula and a retinal detachment with no identifiable retinal break and shifting subretinal fluid. Four months prior to presentation, he had traveled to Costa Rica on vacation and…
Importance An outbreak of COVID-19–associated rhino-orbitocerebral mucormycosis (CAM) has occurred in many parts of the world. Although the clinical profile and risk factors for CAM have been studied, cumulative mortality and its risk factors have not. Objective To report the cumulative mortality…
A 12-year-old girl with bilateral panuveitis presented for abnormal gait. Her subsequent workup revealed elevated inflammatory markers and subcentimeter chest and abdominal lymph nodes. What would you do next?
A patient with a history of normal-tension glaucoma and 5 years of latanoprost treatment for an enlarged cup-disc ratio presented with a blurred spot in the central vision of the right eye. What would you do next?
A 49-year-old man with a history of diabetes, hypertension, intravenous drug abuse, and multiple sexual partners presented with painless vision loss in both eyes for 10 days, left eye worse than right eye, and photophobia in both eyes. What would…
A 55-year-old man with advanced primary open-angle glaucoma presented with 1 day of decreased vision and eye pain. He had undergone trabeculectomy and 5-fluorouracil injection 1 month prior. What would you do next?
Importance Astronauts returning from long-duration spaceflight experience ocular remodeling related to cephalad fluid shifts induced by microgravity. It is hypothesized that the absence of diurnal reductions in intracranial pressure in microgravity creates a low but persistent pressure gradient at the posterior…
Importance Open-angle glaucoma may continue to progress despite significant lowering of intraocular pressure (IOP). Preclinical research has suggested that enhancing mitochondrial function and energy production may enhance retinal ganglion cell survival in animal models of glaucoma, but there is scant information…
A man aged 57 years with a history of Crohn disease presents to the emergency department after 3 weeks of bilateral periorbital pain and swelling. Computed tomography of the orbits reveals moderate bilateral lateral rectus muscle enlargement and mild enlargement…
A 49-year-old African American woman has had abnormal retinal findings for at least 10 years. A fundus examination now showed multiple vitelliform lesions involving the macula and superior macula bilaterally. What would you do next?
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