JAMA Oncology

Interstitial Lung Disease Induced by Anti-ERBB2 Antibody-Drug Conjugates

Importance  In the past decade, ERBB2 (formerly HER2)–directed antibody-drug conjugates (ADCs) have substantially changed treatment of both advanced and early-stage ERBB2-positive breast cancer. Novel conjugates are now showing activity in trials of other ERBB2-associated tumors, leading to the recent US Food and…